Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Intranasal lidocaine for the treatment of migraine headache: a randomized, controlled trial.
To evaluate the effect of intranasal lidocaine for immediate relief (5 minutes) of migraine headache pain. ⋯ There was no evidence that intranasal lidocaine provided rapid relief for migraine headache pain in the emergency department setting.
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Randomized Controlled Trial Clinical Trial
LET versus EMLA for pretreating lacerations: a randomized trial.
To compare the anesthetic efficacy of EMLA cream (eutectic mixture of local anesthetics) with that of LET solution (lidocaine, epinephrine, tetracaine) for pretreating lacerations prior to lidocaine injection. ⋯ Pretreatment of simple lacerations with LET or EMLA at the time of patient presentation results in similar amounts of pain of subsequent local infiltration of lidocaine
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Randomized Controlled Trial Clinical Trial
The efficacy of esmolol versus lidocaine to attenuate the hemodynamic response to intubation in isolated head trauma patients.
To assess the effect of esmolol vs lidocaine to attenuate the detrimental rise in heart rate and blood pressure during intubation of patients with isolated head trauma. ⋯ Esmolol and lidocaine have similar efficacies to attenuate moderate hemodynamic response to intubation of patients with isolated head trauma.
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Randomized Controlled Trial Clinical Trial
Adrenocortical dysfunction following etomidate induction in emergency department patients.
To assess adrenocortical function following intravenous etomidate use in emergency department (ED) patients requiring intubation. ⋯ Use of etomidate in ED patients requiring RSI results in adrenocortical dysfunction. However, cortisol levels remain within normal laboratory levels during this period of dysfunction. Adrenocortical dysfunction appears to resolve within 12 hours of a single bolus dose of 0.3 mg/kg etomidate.
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Randomized Controlled Trial Clinical Trial
The effect of lower-extremity position on cerebrospinal fluid pressures.
To determine the effects of lower-extremity positioning on cerebrospinal fluid opening pressure (CSFp). The authors believed that during lumbar puncture (LP), CSFp does not meaningfully decrease when the lower extremities are extended from flexion, as is often suggested. ⋯ Changing lower-extremity position did not meaningfully change mean CSFp. These data do not support the common suggestion that extending the lower extremities during LP meaningfully decreases CSF opening pressures.