American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jan 2013
Multicenter StudyAssociation between obstructive sleep apnea and cancer incidence in a large multicenter Spanish cohort.
Obstructive sleep apnea (OSA) has been associated with increased cancer mortality, but whether it is also associated with cancer incidence is unknown. ⋯ Increased overnight hypoxia as a surrogate of OSA severity was associated with increased cancer incidence. This association seems to be limited to men and patients younger than 65 years of age.
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Am. J. Respir. Crit. Care Med. · Jan 2013
Monitoring of the respiratory muscles in the critically ill.
Evidence has accumulated that respiratory muscle dysfunction develops in critically ill patients and contributes to prolonged weaning from mechanical ventilation. Accordingly, it seems highly appropriate to monitor the respiratory muscles in these patients. ⋯ In our opinion, however, practical issues and the absence of sound scientific data for clinical benefit should not discourage clinicians from having a closer look at respiratory muscle function in critically ill patients. This perspective discusses the latest developments in the field of respiratory muscle monitoring and possible implications of monitoring respiratory muscle function in critically ill patients.
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Am. J. Respir. Crit. Care Med. · Jan 2013
The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age.
The contribution by asthma to the development of fixed airflow obstruction (AO) and the nature of its effect combined with active smoking and atopy remain unclear. ⋯ Active smoking and current clinical asthma both contribute substantially to fixed AO in middle age, especially among those with atopy. The interaction between these factors provides another compelling reason for atopic individuals with current asthma who smoke to quit.