American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Nov 2014
Obstructive Sleep Apnea During REM Sleep and Hypertension: Results of the Wisconsin Sleep Cohort.
Obstructive sleep apnea (OSA) is associated with hypertension. ⋯ Our findings indicate that REM OSA is cross-sectionally and longitudinally associated with hypertension. This is clinically relevant because treatment of OSA is often limited to the first half of the sleep period leaving most of REM sleep untreated.
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Am. J. Respir. Crit. Care Med. · Nov 2014
Early Respiratory Infection is Associated with Reduced Spirometry in Children with Cystic Fibrosis.
Pulmonary inflammation, infection, and structural lung disease occur early in life in children with cystic fibrosis. ⋯ The onset of lung disease in infancy, specifically the occurrence of lower respiratory tract infection, is associated with low lung function in young children with cystic fibrosis. Deficits in lung function measured in infancy persist into childhood, emphasizing the need for targeted therapeutic interventions in infancy to maximize functional outcomes later in life.