American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jul 2014
Obstructive Sleep Apnea and Incident Diabetes: A Historical Cohort Study.
Despite emerging evidence that obstructive sleep apnea (OSA) may cause metabolic disturbances independently of other known risk factors, it remains unclear whether OSA is associated with incident diabetes. ⋯ Among people with OSA, and controlling for multiple confounders, initial OSA severity and its physiologic consequences predicted subsequent risk for incident diabetes.
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Am. J. Respir. Crit. Care Med. · Jul 2014
RSV Increases the Virulence of Streptococcus pneumoniae by Binding to PBP1a: a New Paradigm in Respiratory Infection.
Respiratory syncytial virus (RSV) and Streptococcus pneumoniae are major respiratory pathogens. Coinfection with RSV and S. pneumoniae is associated with severe and often fatal pneumonia but the molecular basis for this remains unclear. ⋯ The direct interaction between a respiratory virus protein and the pneumococcus resulting in increased bacterial virulence and worsening disease outcome is a new paradigm in respiratory infection.