American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Sep 2016
Structure and Function of the Kidney in Septic Shock: A Prospective Controlled Experimental Study.
It is unclear how septic shock causes acute kidney injury (AKI) and whether this is associated with histological change. ⋯ In an intensive care-supported model of gram-negative septic shock, early AKI was not associated with changes in renal blood flow, oxygen delivery, or histological appearance. Other mechanisms must contribute to septic AKI.