Journal of the American College of Surgeons
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Randomized Controlled Trial Comparative Study
How does high-concentration supplemental perioperative oxygen influence surgical outcomes after thyroid surgery? A prospective, randomized, double-blind, controlled, monocentric trial.
Recurrent laryngeal nerve palsy (RLNP) and hypoparathyroidism are complications of thyroid surgery. The convalescence can depend on several factors (ie, pain, fatigue, nausea, and vomiting). Supplemental oxygen improves inflammatory and immune function and decreases nausea and vomiting after surgical procedures. We have investigated whether supplemental perioperative oxygen administration could improve surgical outcomes in patients undergoing thyroid surgery. ⋯ Supplemental 80% FiO2 reduced postoperative temporary RLNP and hypoparathyroidism rates and reduced pain, fatigue, nausea, and vomiting after thyroid surgery.
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Comparative Study
Impact of National Cancer Institute Comprehensive Cancer Centers on ovarian cancer treatment and survival.
The regional impact of care at a National Cancer Institute Comprehensive Cancer Center (NCI-CCC) on adherence to National Comprehensive Cancer Network (NCCN) ovarian cancer treatment guidelines and survival is unclear. ⋯ National Cancer Institute Comprehensive Cancer Center status is an independent predictor of adherence to ovarian cancer treatment guidelines and improved ovarian cancer-specific survival. These data validate NCI-CCC status as a structural health care characteristic correlated with superior ovarian cancer quality measure performance. Increased access to NCI-CCCs through regional concentration of care may be a mechanism to improve clinical outcomes.