JNMA; journal of the Nepal Medical Association
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JNMA J Nepal Med Assoc · Jul 2007
Etiological agents of bacteraemia and antibiotic susceptibility pattern in Kathmandu Model Hospital.
The presence of bacteria in blood is simply known as bacteraemia. The main aim of this study is to determine the bacteraemia in patients visiting Kathmandu Model Hospital and antibiotic susceptibility pattern of isolates with special interest on ciprofloxacin. This prospective study was carried out in microbiology laboratory, Kathmandu Model Hospital from April 2005 to June 2005. ⋯ Three isolates of Salmonella typhi were found as multidrug resistant (MDR) whereas no MDR was found in Salmonella paratyphi A. From this it can be concluded that Salmonella bacteraemia is more than other. Although nalidixic acid resistant serovars were isolated, ciprofloxacin resistant serovar were not present.
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To study the clinical profile of Henoch Schönlein Purpura [HSP] in children. A retrospective case series of 30 consecutive children with a diagnosis of HSP, with special focus on clinical manifestations. Two cases with unusual features are described in detail. ⋯ Knee and ankle involvement occurred in more than 3/4th of the patients with arthritis. Vesciculobullous lesions were seen in two patients while one patient had rheumatic fever. Most children with HSP will have classical manifestation of the disease but diagnostic confusion can occur in those with atypical or absent cutaneous features at the onset.
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JNMA J Nepal Med Assoc · Apr 2007
Case ReportsAcute liver failure caused by hepatitis E virus and paracetamol.
Acute liver failure is characterized by severe and sudden liver cell dysfunction leading to hepatic encephalopathy and hepatic coagulopathy in a person without history of liver disease in the past. This catastrophic illness can rapidly progress to coma and death from cerebral edema and multi organ dysfunction. ⋯ This report describes a case of acute liver failure in which probably both the agents were involved. The patient recovered with antidote therapy and maximum supportive care.
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JNMA J Nepal Med Assoc · Apr 2007
Comparative StudyLow birth weight at term: relationship with maternal anthropometry.
The objective of this study was to determine the relationship of maternal anthropometry with low birth weight at term. This study was conducted at the Maternity Hospital, Thapathali, from 6th December 2004 to 30th January 2005. It was a prospective, hospital based, comparative study, carried out in 308 women who had delivered singleton live babies at term. ⋯ On multiple logistic regression analysis, only low maternal weight was powerful enough to remain significant (OR 2.84 95% CI 1.34-5.99). From these results, it can be concluded that low maternal anthropometric measurements have a definite role in causing LBW babies at term. Among the studied variables, maternal weight showed the strongest influence on low birth weight.
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JNMA J Nepal Med Assoc · Jan 2007
Randomized Controlled Trial Comparative StudyComparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2 mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor.
Analgesia during labor provided by two epidural drug regimens was compared in a double blind, randomized, prospective study. Group A (n = 12) received 10 ml bolus doses of 0.1% bupivacaine with butorphanol 2 mg while Group B (n = 8) received 10 ml of 0.25% plain bupivacaine. ⋯ Hemodynamic variables were stable and no adverse neonatal and maternal outcome was observed in both groups. Addition of butorphanol to bupivacaine may be safe alternative to reduce motor block and decrease prolong 2nd stage for epidural labor analgesia.