Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 1998
Arterial oxygen saturation profiles in healthy preterm infants.
To construct a reference range of SpO2 values in healthy preterm infants using a simple data logging device. ⋯ Comparison of an infant's SpO2 profile against this curve may be more helpful in guiding supplemental oxygen treatment in that individual than a figure for a mean SPO2 and its standard deviation.
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Arch. Dis. Child. Fetal Neonatal Ed. · May 1998
Prediction of individual response to postnatal dexamethasone in ventilator dependent preterm infants.
To evaluate factors predictive of individual response to dexamethasone in preterm infants. ⋯ Individual responses to dexamethasone can be partly predicted by gestation, the presence of PIE, and the VI before dexamethasone administration.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 1998
Randomized Controlled Trial Clinical TrialRandomised controlled trial of eutectic mixture of local anaesthetics cream for venepuncture in healthy preterm infants.
To assess the safety and efficacy of EMLA cream (eutectic mixture of local anaesthetics) used to induce surface anaesthesia for venepuncture in healthy preterm infants. ⋯ This study does not support the routine use of EMLA for venepuncture in healthy preterm infants.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialRandomised trial of volume controlled versus time cycled, pressure limited ventilation in preterm infants with respiratory distress syndrome.
Fifty preterm infants weighing 1200 g or more with clinical and radiographic evidence of respiratory distress syndrome, requiring both mechanical ventilation and exogenous surfactant replacement, were randomly allocated to receive either volume controlled ventilation or time cycled, pressure limited ventilation. Tidal volume delivery in each group was deliberately controlled at 5-8 ml/kg so that the only difference between the two groups was the ventilatory modality, the manner in which tidal volume was delivered. The rest of the ventilatory management and clinical care was done according to protocol. ⋯ Infants randomised to volume controlled ventilation met success criteria sooner and had a shorter duration of mechanical ventilation. These babies also had a significantly lower incidence of intraventricular haemorrhages and abnormal periventricular echodensities on ultrasound scans. Volume controlled ventilation seems to be both safe and effective in this group of patients.