The journals of gerontology. Series A, Biological sciences and medical sciences
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J. Gerontol. A Biol. Sci. Med. Sci. · Feb 2014
Racial differences on association of depressive symptoms with combined basic and instrumental activities of daily living.
Depressive symptoms are predictive of multiple degenerative diseases in older age adults. However, the association of depressive symptoms with onset and progression of disability have not been studied. ⋯ Depressive symptoms increased the risk of onset of disability in blacks and whites. This risk tended to increase over time only among whites. A similar race-specific pattern was observed for time-dependent changes due to depressive symptoms in the rate of progression in disability after onset.
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J. Gerontol. A Biol. Sci. Med. Sci. · Jan 2014
Comparative StudyRelationship between obesity and obesity-related morbidities weakens with aging.
A weak relationship exists between obesity and mortality risk in older populations, however, the influence of age on the relationship between obesity and morbidity is unclear. The objective of this study was to determine the influence of age on the relationship between obesity and cardiovascular disease, type 2 diabetes, dyslipidemia, and hypertension. ⋯ A stronger association between obesity and prevalent metabolic conditions exists in young and middle-aged populations than in old and very old populations. Longitudinal studies are needed to verify these findings and to confirm the benefits of weight loss on health across the life span.
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J. Gerontol. A Biol. Sci. Med. Sci. · Dec 2013
Insomnia and health services utilization in middle-aged and older adults: results from the Health and Retirement Study.
Complaints of poor sleep are common among older adults. We investigated the prospective association between insomnia symptoms and hospitalization, use of home health care services, use of nursing homes, and use of any of these services in a population-based study of middle-aged and older adults. ⋯ In this study, insomnia symptoms experienced by middle-aged and older adults were associated with greater future use of costly health services. Our findings raise the question of whether treating or preventing insomnia in older adults may reduce use of and spending on health services among this population.
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Mobility limitations are common and hazardous in community-dwelling older adults but are largely understudied, particularly regarding the role of the central nervous system (CNS). This has limited development of clearly defined pathophysiology, clinical terminology, and effective treatments. Understanding how changes in the CNS contribute to mobility limitations has the potential to inform future intervention studies. ⋯ In addition to greater cross-disciplinary research, there is a need for new approaches to training clinicians and investigators, which integrate concepts and methodologies from individual disciplines, focus on emerging methodologies, and prepare investigators to assess complex, multisystem associations.
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J. Gerontol. A Biol. Sci. Med. Sci. · Oct 2013
Subsyndromal delirium and its determinants in elderly patients hospitalized for acute medical illness.
In older individuals, acute medical illnesses and admission to hospital are often associated with a deterioration of cognitive status, also in the absence of dementia and full-blown delirium. We evaluated the prevalence of subsyndromal delirium (SSD) and its correlates in a sample of elderly medical inpatients. ⋯ Our data suggest that SSD is common in hospitalized older medical inpatients, and low MMSE score might be useful for identification of participants at risk of SSD. Current inflammatory response and reduced O2 arterial saturation were the only independent determinants of cognitive performance in SSD patients.