Journal of pediatric hematology/oncology
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J. Pediatr. Hematol. Oncol. · May 2001
ReviewRhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V.
To review the importance of prognostic factors in developing new protocols for children with rhabdomyosarcoma (RMS). ⋯ Better understanding of biologic differences and new, active agents are needed to improve outcome of patients with unfavorable features at presentation.
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J. Pediatr. Hematol. Oncol. · Jan 1999
Review Case ReportsAnti-s antibody-associated delayed hemolytic transfusion reaction in patients with sickle cell anemia.
Signs and symptoms of delayed hemolytic transfusion reaction (DHTR) may resemble those of vaso-occlusive crises in patients with sickle cell anemia (SCA). The diagnosis of DHTR therefore presents a challenge to the clinician when treating such patients. The current study describes a patient with SCA and DHTR secondary to red cell anti-s antibody, manifesting as painful extremeties, severe hemolytic anemia, and acute oliguric renal failure. ⋯ The possibility of DHTR should be considered in a patient with SCA with hemolytic anemia. Acute renal failure is a rare complication of anti-s antibody-associated DHTR. Such reactions can be successfully managed with exchange transfusion and continuous hemofiltration with dialysis.
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J. Pediatr. Hematol. Oncol. · Nov 1998
Review Case ReportsIntrathecal vincristine: an analysis of reasons for recurrent fatal chemotherapeutic error with recommendations for prevention.
Accidental intrathecal vincristine instillation is usually a fatal error. The authors report an analysis of a patient and suggest means with which to reduce such errors. ⋯ Intrathecal injection of vincristine may be the end-result of a series of systems errors. Protocol recommendations to reduce the likelihood of this error are presented.
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J. Pediatr. Hematol. Oncol. · Jul 1998
Review Case ReportsSpinal canal involvement in infantile myofibromatosis: case report and review of the literature.
An unusual case of infantile myofibromatosis with spinal canal involvement is reported and the literature is reviewed. ⋯ Only six cases of infantile myofibromatosis associated with spinal canal involvement have been reported. Three patients with flaccid paresis of extremities and respiratory distress died in the newborn period. The other three patients showed improvement of the paresis. The prognosis of infantile myofibromatosis without visceral complication is generally good, but neurologic impairment may occur at birth if the spinal cord is compressed.