Neurobiology of learning and memory
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Neurobiol Learn Mem · Jul 1998
ReviewPhysiological memory in primary auditory cortex: characteristics and mechanisms.
"Physiological memory" is enduring neuronal change sufficiently specific to represent learned information. It transcends both sensory traces that are detailed but transient and long-term physiological plasticities that are insufficiently specific to actually represent cardinal details of an experience. The specificity of most physiological plasticities has not been comprehensively studied. ⋯ This model is supported by several recent findings. For example, tone paired with NB stimulation induces associative, specific receptive field plasticity of at least a 24-h duration. We propose that physiological memory in auditory cortex is not "procedural" memory, i.e., is not tied to any behavioral conditioned response, but can be used flexibly.
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Neurobiol Learn Mem · Jul 1998
Review Comparative StudyA comparative perspective on motor learning.
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Neurobiol Learn Mem · Jan 1995
ReviewProperties and mechanisms of long-term synaptic plasticity in the mammalian brain: relationships to learning and memory.
Long-term potentiation (LTP) in the hippocampus and long-term depression (LTD) in the cerebellum are two forms of long-lasting synaptic plasticity that currently serve as our primary experimental models of learning and memory formation in mammals. In recent years, there have been considerable advances in our understanding of the cellular and molecular mechanisms of these and other forms of synaptic plasticity. This article presents an overview of these developments, considers the relationship of long-term synaptic plasticity mechanisms to learning and memory in view of these developments, and suggests future directions for research in this rapidly growing area of neuroscience.