Multiple sclerosis : clinical and laboratory research
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Corrigendum to 25-hydroxyvitamin D in cerebrospinal fluid during relapse and remission of multiple sclerosis by Trygve Holmøy, Stine Marit Moen, Thomas A Gundersen, Michael F Holick, Enrico Fainardi, Massimiliano Castellazzi and Ilaria Casetta. 15(11) 1280-1285 [DOI: 10.1177/1352458509107008].
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Neurofilament light chain (NfL) levels in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients correlate with the degree of neuronal injury. To date, little is known about NfL concentrations in the serum of relapsing remitting multiple sclerosis (RRMS) patients and their relationship with CSF levels and magnetic resonance imaging (MRI) measures of disease severity. We aimed to validate the quantification of NfL in serum samples of RRMS, as a biofluid source easily accessible for longitudinal studies. ⋯ CSF and serum NfL levels were highly correlated, and serum concentrations were increased in RRMS. Serum NfL levels correlated with MRI markers of WM disease severity. Our findings further support longitudinal studies of serum NfL as a potential biomarker of on-going disease progression and as a potential surrogate to quantify effects of neuroprotective drugs in clinical trials.
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In the article The use of gaming technology for rehabilitation in people with multiple sclerosis, DOI: 10.1177/1352458514563593, published in Multiple Sclerosis Volume 21 Issue 4, Table 1 was printed incorrectly. The corrected Table 1 is below:spmsj;22/12/NP9/TABLE11352458515585718T1table1-1352458515585718Table 1. ⋯ Ref. PlatformParticipants and interventionOutcomesPlow and Finlayson31WiiPre-test vs. post-test repeated measures home-based Wii training.
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Corrigendum to Ragheb, S et al. (2011). Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid Multiple Sclerosis Journal 17(07) 819-829. [DOI: 10.1177/1352458511398887].
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Corrigendum to Munger, KL and Ascherio A. (2011). Prevention and treatment of MS: studying the effects of vitamin D Multiple Sclerosis Journal 17(12) 1405-1411. [DOI:10.1177/1352458511425366].