Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.
Limited data compare once-daily options for initial therapy for HIV-1. ⋯ National Institutes of Health.
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Meta Analysis
Meta-analysis: effect of patient self-testing and self-management of long-term anticoagulation on major clinical outcomes.
Anticoagulation with vitamin K antagonists reduces major thromboembolic complications in at-risk patients. With portable monitoring devices, patients can conduct their own international normalized ratio testing and dose adjustment at home. ⋯ U.S. Department of Veterans Affairs Health Services Research and Development Service.
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Long working hours are associated with increased risk for coronary heart disease (CHD). Adding information on long hours to traditional risk factors for CHD may help to improve risk prediction for this condition. ⋯ Medical Research Council; British Heart Foundation; Bupa Foundation; and the National Heart, Lung, and Blood Institute and National Institute on Aging of the National Institutes of Health.