Annals of internal medicine
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Case Reports
Borrelia miyamotoi infection presenting as human granulocytic anaplasmosis: a case report.
The diverse tickborne infections of the northeastern United States can present as undifferentiated flu-like illnesses. In areas endemic for Lyme and other tickborne diseases, patients presenting with acute febrile illness with myalgia, headache, neutropenia, thrombocytopenia, and elevated hepatic aminotransferase levels are presumptively diagnosed as having human granulocytic anaplasmosis (HGA). ⋯ The presence of B. miyamotoi DNA in the peripheral blood and the patients' eventual therapeutic response to doxycycline are consistent with the hypothesis that their illness was due to this newly recognized spirochete. Samples from tick-exposed patients acutely presenting with signs of HGA but who have a delayed response to doxycycline therapy or negative confirmatory test results for HGA should be analyzed carefully for evidence of B. miyamotoi infection.
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Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for HIV. ⋯ The USPSTF recommends that clinicians screen adolescents and adults aged 15 to 65 years for HIV infection. Younger adolescents and older adults who are at increased risk should also be screened. (Grade A recommendation)The USPSTF recommends that clinicians screen all pregnant women for HIV, including those who present in labor who are untested and whose HIV status is unknown. (Grade A recommendation).
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Randomized Controlled Trial Multicenter Study Clinical Trial
Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial.
Short-duration studies show that salsalate improves glycemia in type 2 diabetes mellitus (T2DM). ⋯ Salsalate improves glycemia in patients with T2DM and decreases inflammatory mediators. Continued evaluation of mixed cardiorenal signals is warranted.