Annals of internal medicine
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Randomized Controlled Trial
Daily oral tenofovir and emtricitabine-tenofovir preexposure prophylaxis reduces herpes simplex virus type 2 acquisition among heterosexual HIV-1-uninfected men and women: a subgroup analysis of a randomized trial.
Daily oral preexposure prophylaxis (PrEP) using the antiretroviral tenofovir disoproxil fumarate (TDF) alone or in combination with emtricitabine (FTC-TDF) reduces the risk for HIV-1 acquisition. Tenofovir has in vitro activity against herpes simplex virus type 2 (HSV-2). ⋯ Bill & Melinda Gates Foundation.
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Pelvic examination is often included in well-woman visits even when cervical cancer screening is not required. ⋯ Department of Veterans Affairs.
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Multicenter Study
Interinstitutional variation in management decisions for treatment of 4 common types of cancer: A multi-institutional cohort study.
When clinical practice is governed by evidence-based guidelines and there is consensus about their validity, practice variation should be minimal. For areas in which evidence gaps exist, greater variation is expected. ⋯ National Cancer Institute and National Comprehensive Cancer Network.