Annals of internal medicine
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Review Meta Analysis
Optimal Timing of Antiretroviral Therapy Initiation for HIV-Infected Adults With Newly Diagnosed Pulmonary Tuberculosis: A Systematic Review and Meta-analysis.
Initiation of antiretroviral therapy (ART) during tuberculosis (TB) treatment remains challenging. ⋯ None. (PROSPERO registration: CRD42012001884).
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Review Meta Analysis
Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis.
Guidelines recommend statins as first-line therapy for dyslipidemia. Monoclonal antibodies targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) is a new lipid-lowering approach. ⋯ CRC 1116 Masterswitches in Myocardial Ischemia, German Research Council DFG.
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Randomized Controlled Trial Multicenter Study
Grazoprevir-Elbasvir Combination Therapy for Treatment-Naive Cirrhotic and Noncirrhotic Patients With Chronic Hepatitis C Virus Genotype 1, 4, or 6 Infection: A Randomized Trial.
Novel interferon- and ribavirin-free regimens are needed to treat hepatitis C virus (HCV) infection. ⋯ Merck & Co.