Annals of internal medicine

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• Ann. Intern. Med. · Aug 2020

  Comment

  In patients with ASCVD and elevated LDL-C with maximal statin therapy, inclisiran reduced LDL-C levels at 18 months.

  Ray KK, Wright RS, Kallend D, et al. Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol. N Engl J Med. 2020;382:1507-19. 32187462.

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• Ann. Intern. Med. · Aug 2020

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  In persistent sciatica and lumbar disk herniation, surgery vs. conservative care reduced leg pain at 6 mo.

  Bailey CS, Rasoulinejad P, Taylor D, et al. Surgery versus conservative care for persistent sciatica lasting 4 to 12 months. N Engl J Med. 2020;382:1093-102. 32187469.

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• Ann. Intern. Med. · Aug 2020

  Annals Consult Guys - Cough: Burst Steroids or No Steroids?

  no abstract available

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• Ann. Intern. Med. · Aug 2020

  Comment

  In high-risk patients with acute upper GI bleeding, urgent vs. early endoscopy did not differ for 30-day mortality.

  Lau JY, Yu Y, Tang RS, et al. Timing of endoscopy for acute upper gastrointestinal bleeding. N Engl J Med. 2020;382:1299-308. 32242355.

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• Ann. Intern. Med. · Aug 2020

  Comment

  In older adults, some antidepressants were associated with increased fracture risk.

  Tamblyn R, Bates DW, Buckeridge DL, et al. Multinational investigation of fracture risk with antidepressant use by class, drug, and indication. J Am Geriatr Soc. 2020;68:1494-503. 32181493.

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