Annals of internal medicine
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Randomized Controlled Trial Pragmatic Clinical Trial
Resistance Testing for Management of HIV Virologic Failure in Sub-Saharan Africa : An Unblinded Randomized Controlled Trial.
Virologic failure in HIV predicts the development of drug resistance and mortality. Genotypic resistance testing (GRT), which is the standard of care after virologic failure in high-income settings, is rarely implemented in sub-Saharan Africa. ⋯ The President's Emergency Plan for AIDS Relief and the National Institute of Allergy and Infectious Diseases.
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Imberti JF, Ding WY, Kotalczyk A, et al. Catheter ablation as first-line treatment for paroxysmal atrial fibrillation: a systematic review and meta-analysis. Heart. 2021;107:1630-6. 34261737.
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Despite the central role of primary care in improving health system performance, there are little recent data on how use of primary care and specialists has evolved over time and its implications for the range of care coordination needed in primary care. ⋯ National Institute on Aging.
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Martínez-Lacalzada M, Viteri-Noël A, Manzano L, et al. Predicting critical illness on initial diagnosis of COVID-19 based on easily-obtained clinical variables: development and validation of the PRIORITY model. Clin Microbiol Infect. 2021. [Epub ahead of print]. 34274525.