Annals of internal medicine

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• Ann. Intern. Med. · Jan 2021

  Comment

  Daily aspirin for primary prevention increased risk for major GI bleeding in healthy older adults.

  Mahady SE, Margolis KL, Chan A, et al. Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial. Gut. 2020. [Epub ahead of print.] 32747412.

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• Ann. Intern. Med. · Jan 2021

  Comment

  In adults with hypertension, more- vs. less-intensive BP-lowering treatment reduces orthostatic hypotension.

  Juraschek SP, Hu JR, Cluett JL, et al. Effects of intensive blood pressure treatment on orthostatic hypotension: a systematic review and individual participant-based meta-analysis. Ann Intern Med. 2020. [Epub ahead of print.] 32909814.

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• Ann. Intern. Med. · Jan 2021

  Comment

  Newly prescribed canagliflozin vs. GLP-1 agonists was linked to amputation in older adults with type 2 DM and CVD.

  Fralick M, Kim SC, Schneeweiss S, et al. Risk of amputation with canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study. BMJ. 2020;370:m2812. 32843476.

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• Ann. Intern. Med. · Jan 2021

  Letter

  Reduced In-Person and Increased Telehealth Outpatient Visits During the COVID-19 Pandemic.

  no abstract available

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• Ann. Intern. Med. · Jan 2021

  Comment

  Low-dose colchicine reduced risk for cardiovascular events in chronic coronary disease.

  Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in patients with chronic coronary disease. N Engl J Med. 2020;383:1838-47. 32865380.

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