Annals of internal medicine
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Review Meta Analysis
Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain : A Systematic Review and Meta-analysis.
The comparative benefits and harms of opioids for musculoskeletal pain in the emergency department (ED) are uncertain. ⋯ None. (PROSPERO: CRD42021275293).
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Comment Meta Analysis
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding.
Kurlander JE, Barnes GD, Fisher A, et al. Association of antisecretory drugs with upper gastrointestinal bleeding in patients using oral anticoagulants: a systematic review and meta-analysis. Am J Med. 2022;135:1231-43.e8. 35679879.
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Cancer screening should be recommended only when the balance between benefits and harms is favorable. This review evaluated how U.S. cancer screening guidelines reported harms, within and across organ-specific processes to screen for cancer. ⋯ National Cancer Institute.