Annals of internal medicine

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• Ann. Intern. Med. · Sep 2023

  Comment

  In COPD with type 2 inflammation despite inhaled triple therapy, dupilumab safely reduced exacerbations.

  Bhatt SP, Rabe KF, Hanania NA, et al; BOREAS Investigators. Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts. N Engl J Med. 2023;389;205-214.37272521.

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• Ann. Intern. Med. · Sep 2023

  Comment

  In treatment-resistant major depression, ketamine was noninferior to ECT for treatment response.

  Anand A, Mathew SJ, Sanacora G, et al. Ketamine versus ECT for nonpsychotic treatment-resistant major depression. N Engl J Med. 2023;388:2315-2325. 37224232.

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• Ann. Intern. Med. · Sep 2023

  Comment

  In moderate-to-severe Crohn disease, upadacitinib increased clinical remission at 12 and 52 wk.

  Loftus EV Jr, Panés J, Lacerda AP, et al. Upadacitinib induction and maintenance therapy for Crohn's disease. N Engl J Med. 2023;388:1966-1980. 37224198.

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• Ann. Intern. Med. · Sep 2023

  Editorial Comment

  Preparing the United States for the Next Pandemic.

  no abstract available

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• Ann. Intern. Med. · Sep 2023

  Comment Letter

  The Use of Opioids in the Management of Chronic Pain.

  no abstract available

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