Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Endoscopic En Bloc Versus Piecemeal Resection of Large Nonpedunculated Colonic Adenomas : A Randomized Comparative Trial.
Endoscopic resection of adenomas prevents colorectal cancer, but the optimal technique for larger lesions is controversial. Piecemeal endoscopic mucosal resection (EMR) has a low adverse event (AE) rate but a variable recurrence rate necessitating early follow-up. Endoscopic submucosal dissection (ESD) can reduce recurrence but may increase AEs. ⋯ French Ministry of Health.
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Meta Analysis
Development and Validation of a Protein Risk Score for Mortality in Heart Failure : A Community Cohort Study.
Heart failure (HF) is a complex clinical syndrome with high mortality. Current risk stratification approaches lack precision. High-throughput proteomics could improve risk prediction. Its use in clinical practice to guide the management of patients with HF depends on validation and evidence of clinical benefit. ⋯ Division of Intramural Research at the National Heart, Lung, and Blood Institute of the National Institutes of Health.