Annals of internal medicine
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Randomized Controlled Trial
In subclinical AF, apixaban vs. aspirin reduced stroke or systemic embolism at 3.5 y, regardless of duration of recent subclinical AF episodes.
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
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Review Meta Analysis
Anticoagulation Among Patients Hospitalized for COVID-19 : A Systematic Review and Prospective Meta-analysis.
Reported results of clinical trials assessing higher-dose anticoagulation in patients hospitalized for COVID-19 have been inconsistent. ⋯ No direct funding. (PROSPERO: CRD42020213461).
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Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease in the United States. It is characterized by steatosis in the liver and is potentially reversible. Risk factors include obesity, type 2 mellitus, and other metabolic disorders. ⋯ Diet, exercise, and weight loss are the cornerstones of management. Although only 1 medication has been approved for treatment of MASH, other pharmacotherapies and surgeries that aid weight loss and optimize metabolic risk factors can be used. Early diagnosis and intervention are important to prevent progression to cirrhosis and its complications, including cancer.