Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Hospital-Level Care at Home for Acutely Ill Adults: A Randomized Controlled Trial.
Substitutive hospital-level care in a patient's home may reduce cost, health care use, and readmissions while improving patient experience, although evidence from randomized controlled trials in the United States is lacking. ⋯ Partners HealthCare Center for Population Health and internal departmental funds.
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Multicenter Study
Preoperative N-Terminal Pro-B-Type Natriuretic Peptide and Cardiovascular Events After Noncardiac Surgery: A Cohort Study.
Preliminary data suggest that preoperative N-terminal pro-B-type natriuretic peptide (NT-proBNP) may improve risk prediction in patients undergoing noncardiac surgery. ⋯ Canadian Institutes of Health Research.
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Randomized Controlled Trial Multicenter Study
Disease-Modifying Effects of a Novel Cathepsin K Inhibitor in Osteoarthritis: A Randomized Controlled Trial.
MIV-711 is a novel selective cathepsin K inhibitor with beneficial effects on bone and cartilage in preclinical osteoarthritis models. ⋯ Medivir.
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Multicenter Study
Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial.
The potential role of new oral anticoagulants in antiphospholipid antibody syndrome (APS) remains uncertain. ⋯ Bayer Hispania.
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Multicenter Study Observational Study
Cardiac and Neuromuscular Features of Patients With LMNA-Related Cardiomyopathy.
Mutations in the LMNA (lamin A/C) gene have been associated with neuromuscular and cardiac manifestations, but the clinical implications of these signs are not well understood. ⋯ None.