Annals of internal medicine
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Review Meta Analysis Comparative Study
Biological agents for moderately to severely active ulcerative colitis: a systematic review and network meta-analysis.
Biological agents are emerging treatment options for the management of ulcerative colitis (UC). ⋯ Biological agents are effective treatments for UC, but head-to-head trials are warranted to establish the best therapeutic option.
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Review Meta Analysis
Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis.
Guidelines advocate changes in fatty acid consumption to promote cardiovascular health. ⋯ British Heart Foundation, Medical Research Council, Cambridge National Institute for Health Research Biomedical Research Centre, and Gates Cambridge.
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Review Meta Analysis
Accuracy of fecal immunochemical tests for colorectal cancer: systematic review and meta-analysis.
Performance characteristics of fecal immunochemical tests (FITs) to screen for colorectal cancer (CRC) have been inconsistent. ⋯ National Institute of Diabetes and Digestive and Kidney Diseases and National Cancer Institute.
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Review Meta Analysis
Are metabolically healthy overweight and obesity benign conditions?: A systematic review and meta-analysis.
Recent interest has focused on a unique subgroup of overweight and obese individuals who have normal metabolic features despite increased adiposity. Normal-weight individuals with adverse metabolic status have also been described. However, it remains unclear whether metabolic phenotype modifies the morbidity and mortality associated with higher body mass index (BMI). ⋯ Intramural funds from the Leadership Sinai Centre for Diabetes.
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Review Meta Analysis
Risk-benefit profile of long-term dual- versus single-antiplatelet therapy among patients with ischemic stroke: a systematic review and meta-analysis.
Dual-antiplatelet regimens for prevention of recurrent stroke promote antithrombotic effects but may increase the risk for hemorrhage. ⋯ Chang Gung Memorial Hospital.