Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial.
A prophylactic HIV-1 vaccine is a global health priority. ⋯ International AIDS Vaccine Initiative, National Institutes of Health, Ragon Institute, Crucell Holland.
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Randomized Controlled Trial Multicenter Study
Acupuncture for Menopausal Hot Flashes: A Randomized Trial.
Hot flashes (HFs) affect up to 75% of menopausal women and pose a considerable health and financial burden. Evidence of acupuncture efficacy as an HF treatment is conflicting. ⋯ National Health and Medical Research Council.
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Randomized Controlled Trial Multicenter Study Comparative Study
Laparoscopic Lavage for Perforated Diverticulitis With Purulent Peritonitis: A Randomized Trial.
Perforated diverticulitis with purulent peritonitis has traditionally been treated with open colon resection and stoma formation with risk for reoperations, morbidity, and mortality. Laparoscopic lavage alone has been suggested as definitive treatment. ⋯ ALF; Sahlgrenska University Hospital, Gothenburg.
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Randomized Controlled Trial Multicenter Study
Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial.
Effective, pangenotypic treatments for hepatitis C virus (HCV) infection are needed. ⋯ Gilead Sciences.
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Randomized Controlled Trial Multicenter Study
Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection: A Randomized Trial.
Effective treatment options are needed for patients with genotype 1 or 3 hepatitis C virus (HCV) infection in whom previous therapy has failed. ⋯ Gilead Sciences.