Annals of internal medicine
-
Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial.
New treatment modalities are urgently needed for patients with COVID-19. The World Health Organization (WHO) Solidarity trial showed no effect of remdesivir or hydroxychloroquine (HCQ) on mortality, but the antiviral effects of these drugs are not known. ⋯ National Clinical Therapy Research in the Specialist Health Services, Norway.
-
Randomized Controlled Trial Multicenter Study Comparative Study
Effect of Bedside Compared With Outside the Room Patient Case Presentation on Patients' Knowledge About Their Medical Care : A Randomized, Controlled, Multicenter Trial.
Although bedside case presentation contributes to patient-centered care through active patient participation in medical discussions, the complexity of medical information and jargon-induced confusion may cause misunderstandings and patient discomfort. ⋯ Swiss National Foundation (10531C_ 182422).
-
Randomized Controlled Trial Multicenter Study
Effect of Sotagliflozin on Total Hospitalizations in Patients With Type 2 Diabetes and Worsening Heart Failure : A Randomized Trial.
In the SOLOIST-WHF (Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure) trial, sotagliflozin, a sodium-glucose cotransporter-1 and sodium-glucose cotransporter-2 inhibitor, reduced total occurrences of cardiovascular deaths, hospitalizations for heart failure, and urgent visits for heart failure relative to placebo by 33%. ⋯ Sanofi at initiation and Lexicon Pharmaceuticals at completion.
-
Randomized Controlled Trial
Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial.
Central obesity is a major manifestation of metabolic syndrome, which is a common health problem in middle-aged and older adults. ⋯ Health and Medical Research Fund.
-
Letter Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial
Food Insecurity and Weight Loss in an Underserved Primary Care Population: A Post Hoc Analysis of a Cluster Randomized Trial.