Annals of internal medicine
-
Randomized Controlled Trial
Preventing Hospital Readmission for Patients With Comorbid Substance Use Disorder : A Randomized Trial.
Hospitalized patients with comorbid substance use disorders (SUDs) are at high risk for poor outcomes, including readmission and emergency department (ED) use. ⋯ National Institute on Drug Abuse.
-
Randomized Controlled Trial Multicenter Study
Is Comprehensive Geriatric Assessment Admission Avoidance Hospital at Home an Alternative to Hospital Admission for Older Persons? : A Randomized Trial.
Delivering hospital-level care with comprehensive geriatric assessment (CGA) in the home is one approach to deal with the increased demand for bed-based hospital care, but clinical effectiveness is uncertain. ⋯ The National Institute for Health Research Health Services and Delivery Research Programme (12/209/66).
-
Randomized Controlled Trial Multicenter Study
The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin-Detected Pregnancy, Pregnancy Loss, and Live Birth : Per Protocol Analysis of a Randomized Trial.
A previous large randomized trial indicated that preconception-initiated low-dose aspirin (LDA) therapy did not have a positive effect on pregnancy outcomes. However, this trial was subject to nonadherence, which was not taken into account by the intention-to-treat approach. ⋯ National Institutes of Health.
-
Randomized Controlled Trial Multicenter Study
A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine.
Zika virus (ZIKV) may cause severe congenital disease after maternal-fetal transmission. No vaccine is currently available. ⋯ Janssen Vaccines and Infectious Diseases.
-
Randomized Controlled Trial Multicenter Study
The Use of Rifaximin in the Prevention of Overt Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt : A Randomized Controlled Trial.
The efficacy of rifaximin in the secondary prevention of overt hepatic encephalopathy (HE) is well documented, but its effectiveness in preventing a first episode in patients after transjugular intrahepatic portosystemic shunt (TIPS) has not been established. ⋯ French Public Health Ministry.