Annals of internal medicine
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Randomized Controlled Trial
Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion-Synovitis of Knee Osteoarthritis : A Randomized Trial.
Current pharmacologic therapies for patients with osteoarthritis are suboptimal. ⋯ University of Tasmania and Natural Remedies Private Limited.
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Randomized Controlled Trial
Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension: A Randomized Clinical Trial.
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Randomized Controlled Trial Multicenter Study
Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial.
No effective oral therapy exists for early coronavirus disease 2019 (COVID-19). ⋯ Private donors.
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Randomized Controlled Trial
Effects of Interleukin-1β Inhibition on Incident Hip and Knee Replacement: Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial.
Osteoarthritis is a common inflammatory disorder with no disease-modifying therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large joint osteoarthritis is unclear. ⋯ Novartis Pharmaceuticals.
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Randomized Controlled Trial Multicenter Study Comparative Study
Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes: Results From a Randomized Trial.
The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown. ⋯ German Center for Cardiovascular Research and Deutsches Herzzentrum München.