Annals of internal medicine
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Randomized Controlled Trial Multicenter Study
Poxvirus Vectored Cytomegalovirus Vaccine to Prevent Cytomegalovirus Viremia in Transplant Recipients: A Phase 2, Randomized Clinical Trial.
Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). ⋯ National Cancer Institute and Helocyte.
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Randomized Controlled Trial Multicenter Study Comparative Study
Addition of Maraviroc Versus Placebo to Standard Antiretroviral Therapy for Initial Treatment of Advanced HIV Infection: A Randomized Trial.
Patients diagnosed with advanced HIV infection have a poor prognosis despite initiation of combined antiretroviral therapy (c-ART). ⋯ INSERM-ANRS (French National Agency for Research on AIDS).
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Randomized Controlled Trial Multicenter Study
Hospital-Level Care at Home for Acutely Ill Adults: A Randomized Controlled Trial.
Substitutive hospital-level care in a patient's home may reduce cost, health care use, and readmissions while improving patient experience, although evidence from randomized controlled trials in the United States is lacking. ⋯ Partners HealthCare Center for Population Health and internal departmental funds.
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Randomized Controlled Trial Multicenter Study
Disease-Modifying Effects of a Novel Cathepsin K Inhibitor in Osteoarthritis: A Randomized Controlled Trial.
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Randomized Controlled Trial
Effect of Electronic Health Record-Based Coaching on Weight Maintenance: A Randomized Trial.
Weight regain after intentional loss is common. Most evidence-based weight management programs focus on short-term loss rather than long-term maintenance. ⋯ Agency for Healthcare Research and Quality and National Institutes of Health.