Annals of surgery
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Review Comparative Study
Systematic review of surgical options for idiopathic megarectum and megacolon.
A subgroup of patients with intractable constipation has persistent dilatation of the bowel, which in the absence of an organic cause is termed idiopathic megabowel (IMB). The aim of this systematic review was to evaluate the published outcome data of surgical procedures for IMB in adults. ⋯ Outcome data of surgery for IMB must be interpreted with extreme caution due to limitations of included studies. Recommendations based on firm evidence cannot be given, although colectomy appears to be the optimum procedure in patients with a nondilated rectum, restorative proctocolectomy the most suitable in those with dilatation of the colon and rectum, and VRR in those patients with dilatation confined to the rectum. Appropriately designed studies are required to make valid comparisons of the different procedures available.
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Comparative Study
The severity of injury in children resulting from acts against civilian populations.
To characterize the injuries to children by acts against civilian populations (AACP). ⋯ AACP cause significant morbidity and mortality in children, especially adolescents. Injury severity is significantly higher among children who are injured by explosions rather than by shootings.
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Randomized Controlled Trial Comparative Study Clinical Trial
Glutamine supplementation of parenteral nutrition does not improve intestinal permeability, nitrogen balance, or outcome in newborns and infants undergoing digestive-tract surgery: results from a double-blind, randomized, controlled trial.
To assess the effect of isocaloric isonitrogenous parenteral glutamine supplementation on intestinal permeability and nitrogen loss in newborns and infants after major digestive-tract surgery. ⋯ In newborns and infants after major digestive-tract surgery, we did not identify beneficial effects of isonitrogenous, isocaloric glutamine supplementation of parenteral nutrition. Glutamine supplementation in these patients therefore is not warranted until further research proves otherwise.
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Comparative Study
Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysis.
To determine if brief alcohol interventions in trauma centers reduce health care costs. ⋯ Screening and brief intervention for alcohol problems in trauma patients is cost-effective and should be routinely implemented.
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Comment Letter Comparative Study
Is primary resection and salvage transplantation for hepatocellular carcinoma a reasonable strategy?