Annals of surgery
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The purpose of this study was to identify gene-expression changes in leg muscle for up to 24 months after a severe thermal injury. ⋯ Gene changes can be identified for up to 18 months after burn but not at 24 months. These gene changes may provide information concerning what genes in skeletal muscle contribute to recovery from burn trauma.
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Comparative Study
Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysis.
To determine if brief alcohol interventions in trauma centers reduce health care costs. ⋯ Screening and brief intervention for alcohol problems in trauma patients is cost-effective and should be routinely implemented.
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Comparative Study
A comparison of ductoscopy-guided and conventional surgical excision in women with spontaneous nipple discharge.
Radiologic imaging is routinely used to evaluate women with spontaneous nipple discharge (SND), but definitive diagnosis is usually only achieved by surgical terminal duct excision (TDE). Ductoscopy has been reported to result in improved localization of intraductal lesions and may avoid surgery in women with endoscopically normal ducts. ⋯ Ductoscopy identifies intraductal lesions in a high proportion of women with SND, and it may contribute to more accurate resection of these. A prospective study is required to obtain an unbiased assessment of these possible advantages.
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Comparative Study
Current perceptions regarding surgical margin status after breast-conserving therapy: results of a survey.
The surgical margin status after breast-conserving surgery is considered the strongest predictor for local failure. The purpose of this study is to survey how radiation oncologists in North America (NA) and Europe define negative or close surgical margins after lumpectomy and to determine the factors that govern the decision to recommend reexcision based on the margins status. ⋯ This study revealed significant variation in the perception of negative and close margins among radiation oncologists in NA and Europe. Given these findings, a universal definition of negative margins and consistent recommendations for reexcision are needed.
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Comment Letter Comparative Study
Is primary resection and salvage transplantation for hepatocellular carcinoma a reasonable strategy?