Annals of surgery
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Comparative Study
Minimally Invasive Versus Open Pancreaticoduodenectomy: A Propensity-Matched Study From a National Cohort of Patients.
To compare the perioperative outcomes of minimally invasive pancreaticoduodenectomy (MIPD) in comparison with open pancreaticoduodenectomy (OPD) in a national cohort of patients. ⋯ MIPD had an equivalent morbidity and mortality rate to OPD, with the benefit of a decreased rate of prolonged length of stay, though this is partially offset by an increased readmission rate.
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To assess how virtual hepatectomy (VH), conducted using surgical planning software, influences the outcomes of liver surgery. ⋯ VH in LDLT allows double equipoise for the recipient and donor by optimizing decision-making on graft selection and venous reconstruction. VH offers a chance for radical hepatectomy even in HCC patients with impaired liver function and CRLM patients with advanced tumors, without compromising survival.
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To evaluate the diagnostic potential of smooth muscle protein of 22 kDa (SM22) as plasma biomarker for the detection of transmural intestinal ischemia. ⋯ This study shows that SM22 is released into the circulation upon severe ischemia of the intestinal muscle layers. Plasma levels of SM22 are potentially useful for the detection of transmural intestinal damage.
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: With increased focus on the potential harms of surgical opioid prescribing, surgeons should be cognizant of the risk of opioid-related adverse events in their patients, including overdose. Risk factors for overdose may be more prevalent than surgeons think, and include high current opioid use, previous or existing substance use disorder, history of overdose, or certain medical comorbidities. The first step to protecting surgical patients from opioid overdose is adequate screening for risk factors; appropriate patient counseling and prudent prescribing practices can then help protect at-risk patients.