Annals of surgery
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Multicenter Study
Management of Pathogenic CDH1 Variant Carriers within the FREGAT Network: A multicentric Retrospective Study.
To describe the management of pathogenic CDH1 variant carriers (pCDH1vc) within the FREGAT (FRench Eso-GAsTric tumor) network. Primary objective focused on clinical outcomes and pathological findings, Secondary objective was to identify risk factor predicting postoperative morbidity (POM). ⋯ Among pCDH1vc, index cases carry a dismal prognosis. The risk of cancer among patients undergoing PTG remained high and unpredictable and has to be balanced with the morbidity and functional consequence of PTG.
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Multicenter Study
Machine Learning Risk Prediction Model of 90-day Mortality after Gastrectomy for Cancer.
To develop and validate a risk prediction model of 90-day mortality (90DM) using machine learning in a large multicenter cohort of patients undergoing gastric cancer resection with curative intent. ⋯ A robust clinical model for predicting the risk of 90DM after surgery of gastric cancer was developed. Its use may aid patients and surgeons in making informed decisions.
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Multicenter Study
Long-term Satisfaction with Roux-en-Y Gastric Bypass Surgery: Results from a Multicenter Prospective Cohort Study.
The aim of this study was to examine change in overall satisfaction with Roux-en-Y gastric bypass (RYGB) surgery over 3 to 7 years post-surgery and identify pre-surgery predictors and post-surgery factors associated with not being satisfied. ⋯ Level of satisfaction with RYGB surgery significantly decreased 3 to 7 years following surgery. Several pre- and post-surgery characteristics were associated with not being satisfied with surgery and provide potentially useful insight into individual patient experiences following RYGB. Knowledge of these characteristics may be useful in communication between surgeons and patients regarding post-surgical expectations and the impact of surgery on patients' lives.
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To compare the short-term outcomes, surgery burden, and technical performance of robotic total gastrectomy (RTG) and laparoscopic total gastrectomy (LTG) for gastric cancer (GC). ⋯ In complex total gastrectomy for GC, compared with traditional laparoscopic surgery, robotic surgery provides a technically superior operative environment and reduces surgeon workload at high-volume specialized institutions.
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Multicenter Study
Clinical Outcomes after Total Pancreatectomy: A Prospective Multicenter Pan-European Snapshot Study.
To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. ⋯ This pan-European prospective snapshot study found a 5% inhospital mortality after TP. The identified predictors for mortality, including low-volume centers, age, and increased blood loss, may be used to improve outcomes.