Annals of surgery
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Randomized Controlled Trial Multicenter Study Observational Study
Surgical Complications in a Multicenter Randomized Trial Comparing Preoperative Chemoradiotherapy and Immediate Surgery in Patients With Resectable and Borderline Resectable Pancreatic Cancer (PREOPANC Trial).
To investigate the effect of preoperative chemoradiotherapy on surgical complications in patients after pancreatic resection for (borderline-)resectable pancreatic cancer. ⋯ Preoperative chemoradiotherapy did not increase the incidence of surgical complications or mortality and reduced the rate of postoperative pancreatic fistula after resection in patients with (borderline-)resectable pancreatic cancer.
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Randomized Controlled Trial Multicenter Study
The Conventional Technique Versus the No-Touch Isolation Technique for Primary Tumor Resection in Patients With Colon Cancer (JCOG1006): A Multicenter, Open-Label, Randomized, Phase III Trial.
This phase III trial evaluated whether the no touch was superior to the conventional in patients with cT3/T4 colon cancer. ⋯ The present study failed to confirm the superiority of the no touch.
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Randomized Controlled Trial Multicenter Study
Antiseptic Skin Agents to Prevent Surgical Site Infection after Incisional Surgery: A Randomized, Three-Armed Combined Non-Inferiority and Superiority Clinical Trial (NEWSkin Prep Study).
To compare SSI rates between the skin preparation agents: PI-Aq, povidone-iodine with alcohol (PI-Alc), and chlorhexidine with alcohol (C-Alc). ⋯ PI-Alc is non-inferior to C-Alc and not superior to PI-Aq. This is at odds with current guidelines that suggest alcohol-based chlorhexidine solutions should routinely be used for surgical skin preparation.
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Randomized Controlled Trial
Direct Oral Feeding After a Minimally Invasive Esophagectomy: A Single-Center Prospective Cohort Study.
The aim of this single-center cohort study was to compare direct oral feeding (DOF) to standard of care after a minimally invasive esophagectomy (MIE) performed in a center with a stable and acceptable postoperative complication rate. ⋯ Direct oral feeding following a MIE results in a faster time to functional recovery and lower 30-day postoperative complication rate compared to patients that were orally fasted.
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Randomized Controlled Trial
A Health Economic Evaluation of the World Health Organization Surgical Safety Checklist: A Single Center Assessment.
To evaluate cost-effectiveness of the WHO Surgical Safety Checklist. ⋯ Implementation of the WHO checklist was a cost-effective strategy for improving surgical safety.