Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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The aim of this study was to investigate the chest CT findings of coronavirus disease 2019 (COVID-19) from January to February 2020. CT features of six cases, confirmed by reverse transcription polymerase chain reaction (RT-PCR) with COVID-19 disease, were evaluated. Of the six patients, one patient had normal scan. ⋯ While one patient had enlarged mediastinal nodes, no one had pleural effusion. CT can be used as the first choice for early diagnosis of COVID-19 pneumonia. Key Words: Pneumonia, Lung CT scan, COVID-19, Coronavirus infection.
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J Coll Physicians Surg Pak · Jun 2020
Insight into COVID-19 Responses and Initiatives from Pakistan.
The coronavirus pandemic is a rapidly evolving outbreak that has tremendously distressed people worldwide. The paper aims to present some key rapid responses and initiatives to COVID-19 undertaken in Pakistan. The information has been gathered by reviewing material and documents pertinent to COVID-19 in the context of Pakistan. ⋯ The government has launched initiatives, like Ehsaas cash dissemination programme, for the underprivileged families to address their basic needs; and philanthropic organisations are also coming forward to support these families. The spread of the pandemic is gradually increasing in Pakistan and we recommend strategies like increasing public awareness campaigns, improving screening capacity, and contact tracing to augment the efficiency of the current responses and initiatives. Key Words: COVID-19, Pakistan, Responses, Initiatives.
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J Coll Physicians Surg Pak · Jun 2020
Case ReportsLate Diagnosis of Paracetamol Poisoning is Always Lethal in Young Adult.
Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses, but hepatotoxicity can occur when misused or after an overdose. The principal toxic metabolite of acetaminophen is N-acetyl-p-benzoquinone imine (NAPQI). Toxicity should be considered in all suspicious cases because of the ubiquitous and initially asymptomatic nature of acetaminophen intoxication. ⋯ Raised liver function tests and elevated prothrombin time were the first indication to this condition, which were proven by detection of acetaminophen in blood and urine by liquid chromatography-mass spectrometry. Further supportive evidence of hepatic necrosis was provided by an ultrasound abdomen, giving the final diagnosis of acetaminophen poisoning causing drug-induced liver injury. Key Words: Acetaminophen poisoning, Drug-induced liver injury, Fulminant hepatic failure, N-acetylcysteine, N-acetyl-p-benzoquinone imine (NAPQI).
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J Coll Physicians Surg Pak · Jun 2020
Observational StudyCorrelation between Overactive Bladder Syndrome and Severity of Coronary Artery Disease in Postmenopausal Women.
To analyse the correlation of overactive bladder (OAB) and severity of coronary artery disease (CAD) by using Gensini score in postmenopausal women. ⋯ The frequency of OAB significantly correlated to severe CAD in postmenopausal women. Moreover, as an additional finding, postmenopausal women with higher LDL levels faced OAB syndrome more frequently. Key Words: Atherosclerosis, Coronary artery disease, Gensini score, Menopause, OAB-V8 form, Overactive bladder.
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J Coll Physicians Surg Pak · Jun 2020
Case ReportsA Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19).
We present a case of a 45-year male with history of fever and cough, followed by shortness of breath, lethargy and confusion at home. He was a known hypertensive, smoker and naswaar addict. He had history of contact with a friend who had recently returned from China, and used to work there as a physician. ⋯ He was managed in intensive care unit (ICU) with broad-spectrum antibiotics, hydroxychloroquine alongwith anticoagulants; but he remained hypoxic with rapidly worsening clinical course, requiring mechanical ventilation; and ultimately succumbed to the disease. Report of COVID-19 PCR came positive after 24 hours. Key words: Coronavirus disease 2019 (COVID-19), Meningoencephalitis, Pneumonia.