Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Oct 2022
Inflammatory Prognostic Index in Metastatic Renal Carcinoma Treated with Nivolumab.
To evaluate the utility of inflammatory prognostic index (IPI), albumin, c-reactive protein (CRP), and lactate dehydrogenase (LDH) as predictive biomarkers of oncologic outcome in metastatic renal cell cancer (mRCC) patients treated with nivolumab. ⋯ Albumin, Immune checkpoint inhibitor, IPI score, Metastatic renal cell carcinoma, Nivolumab, overall survival, Progression-free survival.
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J Coll Physicians Surg Pak · Oct 2022
Observational StudyExternal Iliac Artery Anastomosis and Internal Iliac Artery Anastomosis for Artery anastomosis in Deceased-donor Kidney Transplantation and Multifactorial Analysis of Graft Survival.
To determine the effects of surgical techniques applied to arterial anastomosis for kidney transplantation on the graft outcome. ⋯ Kidney transplantation, Surgical anastomosis, Delayed graft function, Graft survival.
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J Coll Physicians Surg Pak · Oct 2022
Repairing Orbital Floor Fracture with Autologous Nasal Septal Cartilage by using Endoscope through Transoral Maxillary Sinus.
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J Coll Physicians Surg Pak · Oct 2022
Laboratory Evaluation and Pathological Features of Bone Marrow Metastasis in Non-haematological Malignancies.
This study aimed to analyse the diagnostic accuracy of different laboratory parameters that can predict bone marrow metastasis. A cross-sectional analytical study was conducted at the Armed Forces Institute of Pathology (AFIP), Rawalpindi from March 2021 to August 2021. Bone marrow aspirates and biopsy procedures were done on 60 newly diagnosed cases of non-haematological malignancies as part of staging. ⋯ Positive radiological findings were detected in only one case with bone marrow metastasis. The elevated level of serum LDH is not only cost-effective but also has high diagnostic accuracy to predict bone marrow metastasis. Key Words: Bone marrow, Biochemical, Lactate dehydrogenase, Metastasis, Non-haematological malignancies.
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J Coll Physicians Surg Pak · Oct 2022
Case ReportsLeiomyosarcoma of Inferior Vena Cava in an Immunocompetent Young-adult Female Patient.
Leiomyosarcoma of the inferior vena cava is an extremely rare malignancy originating from the smooth muscle of the vessel wall, with only a few hundred cases reported in the literature. There are no clear guidelines for treatment, but surgical resection is currently the only curative option. Further research is needed to better understand the disease and guide its management. ⋯ An abdominal computed tomography revealed a mass in relation with the inferior vena cava and hepatic nodules. Histological examination proved it to be a leiomyosarcoma of inferior vena cava with liver metastases. Key Words: Leiomyosarcoma, Inferior vena cava, Sarcoma.