Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Mar 2022
Case ReportsPancreatic Acinar Cell Carcinoma Presenting with Diffuse Pancreatic Enlargement.
Pancreatic acinar cell carcinoma (PACC) is a rare tumor of the exocrine pancreas. It accounts for only 1% of all pancreatic malignancies. A 39-year woman sought treatment for repeated abdominal pain and jaundice. ⋯ PACC very rarely presents with diffuse enlargement of the pancreas. This case illustrates a rare presentation of PACC with diffuse pancreatic enlargement, which was effectively treated with gemcitabine and albumin paclitaxel chemotherapy. Key Words: Pancreatic acinar cell carcinoma, Positron emission tomography/computed tomography, Chemotherapy.
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J Coll Physicians Surg Pak · Mar 2022
Case ReportsScabies Surrepticius (Bullous Scabies) Presenting as Bullous Impetigo in a Child.
Bullous scabies (BS) is a rare and atypical presentation of scabies, usually affecting elderly males during the seventh decade of life. BS is characterised by intense pruritic eruptions, nocturnal itch, and characteristic blisters with or without burrows in scabies-prone areas. The scabies lesions might predispose patients to bacterial super-infections, resulting in bullae formation similar to bullous impetigo. ⋯ We, herein, report a case of BS in an eight-year boy from Pakistan, treated successfully with 5% topical permethrin and 2% mupirocin. Complete healing was noted within four weeks with no recurrence at two months follow-up. Key Words: Scabies, Bullous, Child, Diagnosis, Treatment.
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J Coll Physicians Surg Pak · Mar 2022
Relationships among Immune Score, TCF21 Methylation, Risk-factor Level, and Prognosis in Prostate Cancer.
To determine whether the immune score and methylation levels of transcription factor 21 (TCF21) could be used as independent diagnostic indicators and prognostic predictors in prostate cancer (PCA). ⋯ The immune score and TCF21 methylation could be used as independent indicators for the diagnosis and prognosis of PCA. Key Words: Prostatic neoplasms, Immunity cellular, DNA methylation.
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J Coll Physicians Surg Pak · Mar 2022
Observational StudyElectrophysiological Pattern and Predictors of Functional Outcome of Patients with Guillain Barre Syndrome at a Tertiary Care Hospital in Pakistan.
To determine electrophysiological pattern and predictors of functional outcomes of patients with Gullain Barre Syndrome (GBS) at a tertiary care hospital. ⋯ In this study population, AIDP was the most common variant with good prognosis and AMAN variant had the worst prognosis. Key Words: Guillain Barre syndrome (GBS), Acute inflammatory demyelinating polyneuropathy (AIDP), Acute motor axonal neuropathy (AMAN), Peripheral neuropathy, Lower limb weakness, Acute motor and sensory axonal neuropathy (AMSAN), Sensory neuropathy, Autoimmune disease.
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J Coll Physicians Surg Pak · Mar 2022
Observational StudyIntralesional Epidermal Growth Factor for Diabetic Foot Ulcers.
To determine the role of the intralesional recombinant epidermal growth factor (rEGF) in the healing and prevention of extremity amputation in advanced diabetic foot ulcer patients. ⋯ Recombinant epidermal growth factor is highly effective for the treatment of diabetic foot ulcers and prevention of extremity amputation. Intralesional rEGf provides efficient and safe wound healing/closure in patients with diabetic foot ulcers. Key Words: Amputation, Epidermal growth factor, Diabetic foot, Wound healing.