Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Mar 2023
Haematopoietic Stem Cell Transplantation (HSCT) for Primary Immune System Disorders in Children: A Single Centre Experience.
To determine the outcomes of allogeneic HSCT in children with primary immune system disorders (PID). ⋯ Immune deficiency, Severe combined immunodeficiency, Haematopoietic stem cell transplantation.
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J Coll Physicians Surg Pak · Mar 2023
Development and Validation of In-house HEp-2 Cell Slides for Detection of Antinuclear Antibodies (ANA) by Indirect Immunofluorescence.
To develop and validate in-house HEp-2 cell slides for the detection of ANA by indirect immunofluorescence. ⋯ Antinuclear antibodies (ANA), Human epithelial type-2 (HEp-2), Immunofluorescence.
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J Coll Physicians Surg Pak · Mar 2023
Observational StudyThe Effect of Ligamentotaxis on Clinical and Radiological Outcomes in Thoracolumbar Burst Fractures with High McCormack Grade.
The aim of this study was to investigate the effect of ligamentotaxis performed in combination with the posterior surgical approach in thoracic and lumbar burst fractures due to high-energy trauma with high McCormack scores (≥7). This observational study was conducted at the University of Health Sciences from January 2015 to December 2020. Medical records of 16 patients were retrospectively evaluated. ⋯ Ligamentotaxis effectively increased the spinal canal diameter and provided vertebral height restoration and kyphosis angle correction in thoracolumbar burst fractures with a high McCormack score. However, no significant neurological improvement was observed in cases with neurological deficits, although laminectomy was performed with ligamentotaxis. Key Words: Ligamentotaxis, Lumbar vertebrae, Spine, Thoracic vertebrae, Thoracolumbar burst fractures, Trauma.
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J Coll Physicians Surg Pak · Mar 2023
Comparison of the Impact of SGLT2-Inhibitors and Exenatide on Body Fat Composition.
To investigate the effect of SGLT2-i and GLP-1RA as an add-on therapy to metformin on weight loss and body composition, and to compare their effects on glucose and lipid parameters. ⋯ Type 2 diabetes mellitus, Obesity, GLP-1 receptor, SGLT2 inhibitor, Body fat distribution, Visceral adiposity.
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J Coll Physicians Surg Pak · Mar 2023
Trajectory of Anxiety, Depression and Quality of Life in Ankylosing Spondylitis: A Descriptive Study.
To investigate anxiety, depression, and health-related quality of life (HRQoL) over 15 years and associations between demographic, disease-related variables, anxiety and depression, and HRQoL in patients with AS. ⋯ Ankylosing spondylitis, Anxiety, Depression, Disease activity, Quality of life.