Respirology : official journal of the Asian Pacific Society of Respirology
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Randomized Controlled Trial
Nintedanib in Japanese patients with idiopathic pulmonary fibrosis: A subgroup analysis of the INPULSIS® randomized trials.
Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive fibrosing interstitial pneumonia. Nintedanib significantly reduced the annual rate of decline in forced vital capacity (FVC) compared with placebo in patients with IPF in two replicate trials (INPULSIS®). We examined the efficacy and safety of nintedanib in Japanese patients. ⋯ The present results indicate that the efficacy and safety of nintedanib in Japanese patients are comparable with those in the overall population.