Aesthetic surgery journal
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Aesthetic surgery journal · Aug 2013
Randomized Controlled TrialTopical lidocaine enhanced by laser pretreatment: a safe and effective method of analgesia for facial rejuvenation.
Injectable forms of anesthesia for nonsurgical facial rejuvenation, although efficacious, are uncomfortable for the patient. Preclinical studies have demonstrated that laser pretreatment at low energies enhances absorption of topical lidocaine. ⋯ Data from this study demonstrate that topical anesthetic for facial rejuvenation can be enhanced with laser pretreatment while maintaining safe blood serum levels. Further studies should examine optimal application amount and time to allow safe multipass facial rejuvenation without the need for invasive nerve blocks.
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Aesthetic surgery journal · May 2012
Randomized Controlled Trial Comparative StudyComparison of five commonly-available, lidocaine-containing topical anesthetics and their effect on serum levels of lidocaine and its metabolite monoethylglycinexylidide (MEGX).
Topical anesthetics are commonly applied for a variety of indications. Several lidocaine-containing topical anesthetics are available for purchase over the counter (OTC). Recently, the authors' group has shown that there is great interindividual discrepancy in the manner in which lidocaine is absorbed and metabolized for even a single OTC product. ⋯ 2.
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Aesthetic surgery journal · Feb 2012
Randomized Controlled Trial Multicenter StudyA two-year observational study assessing the safety of DepoFoam bupivacaine after augmentation mammaplasty.
Two-year safety outcomes in patients who received DepoFoam bupivacaine during two prior breast augmentation studies were evaluated. ⋯ 2.
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Aesthetic surgery journal · Jan 2012
Randomized Controlled Trial Multicenter StudyThe efficacy and safety of DepoFoam bupivacaine in patients undergoing bilateral, cosmetic, submuscular augmentation mammaplasty: a randomized, double-blind, active-control study.
Breast augmentation can result in significant postsurgical pain. ⋯ DepoFoam bupivacaine trended toward benefit versus bupivacaine HCl on most efficacy measures. Due to early termination, the study was underpowered to achieve statistical significance.
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Aesthetic surgery journal · Mar 2009
Randomized Controlled TrialEfficacy of lidocaine for pain control in subcutaneous infiltration during liposuction.
Liposuction remains the most commonly performed aesthetic surgical procedure in the United States. Preoperative infiltration of the subcutaneous tissues with a wetting solution has become standard. These solutions typically contain some amount of lidocaine for pain control. High doses of lidocaine have been demonstrated to be safe, but large amounts of this cardioactive agent during elective cosmetic procedures may be unnecessary. ⋯ Decreasing concentrations of lidocaine in infiltrative wetting solutions did not significantly affect intraoperative anesthesia requirements or postoperative pain with liposuction. Lower concentrations of lidocaine can effectively be used, use of any lidocaine may be unnecessary. Future investigations may examine whether total elimination of lidocaine yields similar results in terms of anesthesia requirements and postoperative pain.