CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
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Practice Guideline Guideline
Hemophilia and von Willebrand's disease: 2. Management. Association of Hemophilia Clinic Directors of Canada.
To present current strategies for the treatment of hemophilia and von Willebrand's disease. ⋯ These recommendations were developed at the request of the Canadian Blood Agency, which funds the provision of all coagulation-factor concentrates for people with congenital bleeding disorders, and were developed and endorsed by the AHCDC and the Medical and Scientific Advisory Committee of the Canadian Hemophilia Society.
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Review Practice Guideline Guideline
Hemophilia and von Willebrand's disease: 1. Diagnosis, comprehensive care and assessment. Association of Hemophilia Clinic Directors of Canada.
To present current strategies for the assessment and comprehensive care of patients with hemophilia and von Willebrand's disease. ⋯ These recommendations were developed at the request of the Canadian Blood Agency, which funds the provision of all coagulation-factor concentrates for people with congenital bleeding disorders, and were developed and endorsed by the AHCDC and the Medical and Scientific Advisory Committee of the Canadian Hemophilia Society.
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Indoor pollution is a major public-health issue, say representatives from government and the medical profession who participated in a recent workshop in Ottawa. Researchers are certain that indoor pollution causes many of the allergy-related problems and asthma, bronchitis, rhinitis, coughing and others respiratory problems experienced by North Americans. They urge physicians to learn about indoor air quality and to educate patients to improve their environment, particularly with respect to second-hand smoke, dust mites and mould.
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Because they are seen as advocates for public health and safety, physicians are also widely believed to be supporters of aggressive gun-control measures, but in reality there are strong feelings on both sides of the issue. "People assume that more gun control will mean less violence, but there are no hard data to support that," says Vancouver psychiatrist Joseph Noone, who argues that Canada already has highly restrictive firearms laws. Other physicians are puzzled by colleagues' opposition to the changes. "I don't understand why it's such a big deal," says Dr. Stephen Corber, medical officer of health for the Ottawa-Carleton region. He argues that registration would not be a deterrent to responsible gun use and ownership.
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Research findings presented at the 10th International Conference on AIDS, held in Yokohama, Japan, in August 1994, indicate that few advances have been made in standard antiretroviral therapy for HIV infection. The perinatal administration of AZT (zidovudine) was reported to reduce transmission of HIV from mother to child, and its use in combination with acyclovir appears to improve survival among patients with advanced disease. Other research has focused on asymptomatic patients with long-standing HIV infection. ⋯ In gene therapy research, one approach involved the genetic alteration of target cells to enable them to render the virus harmless. A second approach consisted of enhancing the function of CD8+ cells to allow them to compensate for dysfunctional CD4+ cells. The author believes that gene therapy may offer the greatest hope of an effective treatment for HIV infection.