CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
The most recent articles from:
CMAJ
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Randomized Controlled Trial Comparative Study
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.
Recent warnings from Health Canada regarding codeine for children have led to increased use of nonsteroidal anti-inflammatory drugs and morphine for common injuries such as fractures. Our objective was to determine whether morphine administered orally has superior efficacy to ibuprofen in fracture-related pain. ⋯ We found no significant difference in analgesic efficacy between orally administered morphine and ibuprofen. However, morphine was associated with a significantly greater number of adverse effects. Our results suggest that ibuprofen remains safe and effective for outpatient pain management in children with uncomplicated fractures.