British journal of anaesthesia
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Randomized Controlled Trial Clinical Trial
Evaluation of effects of magnesium sulphate in reducing intraoperative anaesthetic requirements.
The present randomized, placebo-controlled, double-blind study was designed to assess the effect of peroperatively administered i.v. magnesium sulphate on anaesthetic and analgesic requirements during total i.v. anaesthesia. ⋯ The administration of magnesium led to a significant reduction in the requirements for anaesthetic drugs during total i.v. anaesthesia with propofol, remifentanil and vecuronium.