British journal of anaesthesia
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Randomized Controlled Trial Clinical Trial
Relationship between awareness and middle latency auditory evoked responses during surgical anaesthesia.
Some studies support the view that meaningful auditory input can be processed by the brain during apparent surgical anaesthesia. Consequently, patients may be able to remember some information implicitly after anaesthesia as well through a 'dream-like process' (subconscious awareness). The aim of this study was to investigate the presence of subconscious awareness during anaesthesia and to examine its relationship to the mid-latency auditory evoked responses (MLAERs). ⋯ MLAERs may help to predict subconscious cerebral processing of auditory inputs during anaesthesia.
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Case Reports
Detection of cerebral hypoperfusion with bispectral index during paediatric cardiac surgery.
The bispectral index (BIS) may indicate changes in cerebral activity when the cerebral circulation is affected by acute hypotension. ⋯ Our findings suggest that an acute decrease in BIS during acute hypotension indicates cerebral hypoperfusion, and that cerebral hypoperfusion caused by hypotension may occur frequently during paediatric cardiac surgery.
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The central veins that are usually cannulated are the jugular, subclavian, femoral and brachial. If subclavian catheterization is difficult using surface landmark techniques, we now use ultrasound to catheterize the infraclavicular axillary vein. This approach is not widely used and the ultrasound appearance has not been formally described. We examined the anatomical relationships of the axillary vessels to guide safe cannulation of the axillary vein. ⋯ The axillary vein is an alternative for central venous cannulation and we present an anatomical rationale for its safe use. Less arterio-venous overlap and a greater distance between artery and vein and from vein to rib cage should provide an increased margin of safety for central venous cannulation.
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Non-technical skills are critical for good anaesthetic practice but are not addressed explicitly in normal training. Realization of the need to train and assess these skills is growing, but these activities must be based on properly developed skills frameworks and validated measurement tools. A prototype behavioural marker system was developed using human factors research techniques. The aim of this study was to conduct an experimental evaluation to establish its basic psychometric properties and usability. ⋯ The findings of the evaluation indicated that the ANTS system has a satisfactory level of validity, reliability and usability in an experimental setting, provided users receive adequate training. It is now ready to be tested in real training environments, so that full guidelines can be developed for its integration into the anaesthetic curriculum.
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Randomized Controlled Trial Comparative Study Clinical Trial
Prevention of postoperative nausea and vomiting after spinal morphine for Caesarean section: comparison of cyclizine, dexamethasone and placebo.
Low-dose intrathecal (spinal) morphine (0.1-0.2 mg) for Caesarean section delivers excellent postoperative analgesia but is associated with significant nausea and vomiting. We compared the antiemetic efficacy of cyclizine, dexamethasone, and placebo in this clinical setting. ⋯ We conclude that following spinal morphine 0.2 mg and fentanyl 10 micro g analgesia for Caesarean section, cyclizine 50 mg i.v. reduces the incidence of nausea compared with dexamethasone 8 mg i.v. or placebo. It also lessens the severity of nausea and vomiting, and increases maternal satisfaction in the early postoperative period.