British journal of anaesthesia
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Comparative Study
Comparison of the sedative properties of CNS 7056, midazolam, and propofol in sheep.
CNS 7056 is an esterase-metabolized benzodiazepine sedative currently under development. Its short duration of action would suggest a clinical role similar to midazolam or propofol. ⋯ CNS 7056 is a powerful and short-acting anaesthetic in sheep with respiratory and cardiovascular effects consistent with its sedative/anaesthetic qualities.