British journal of anaesthesia
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The Third National Audit Project of the Royal College of Anaesthetists (NAP3) in 2009 reported the number of central neuraxial blocks (CNBs) performed annually in the UK National Health Service and the incidence of associated major complications. Various methodologies were used to disseminate the results. ⋯ The results of the NAP3 report have been disseminated to the vast majority of UK anaesthetic departments and to the individual anaesthetists supervising the project in those hospitals. NAP3 has led to changes in practice by the majority of hospitals and by many of the anaesthetists surveyed.
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Randomized Controlled Trial Multicenter Study
Impact of preoperative maintenance or interruption of aspirin on thrombotic and bleeding events after elective non-cardiac surgery: the multicentre, randomized, blinded, placebo-controlled, STRATAGEM trial.
Patients receiving anti-platelet agents for secondary cardiovascular prevention frequently require non-cardiac surgery. A substantial proportion of these patients have their anti-platelet drug discontinued before operation; however, there is uncertainty about the impact of this practice. The aim of this study was to compare the effect of maintenance or interruption of aspirin before surgery, in terms of major thrombotic and bleeding events. ⋯ In these at-risk patients undergoing elective non-cardiac surgery, we did not find any difference in terms of occurrence of major thrombotic or bleeding events between preoperative maintenance or interruption of aspirin.