British journal of anaesthesia
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Randomized Controlled Trial
Postoperative impairment of motor function at train-of-four ratio ≥0.9 cannot be improved by sugammadex (1 mg kg-1).
Recovery of train of four ratio to > 0.9 signifies adequate recovery of muscle function after neuromuscular blockade.
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Randomized Controlled Trial
Learning through simulated independent practice leads to better future performance in a simulated crisis than learning through simulated supervised practice.
Learning in a simulated anesthesia crisis is better when the simulation is of independent practice than supervised practice.
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Review Meta Analysis
A Bayesian network meta-analysis on the effect of inodilatory agents on mortality.
Inodilators are commonly used in critically ill patients, but their effect on survival has not been properly studied to date. The objective of this work was to conduct a network meta-analysis on the effects of inodilators on survival in adult cardiac surgery patients, and to compare and rank drugs that have not been adequately compared in head-to-head trials. ⋯ Levosimendan seems to be the most efficacious inodilator to improve survival in cardiac surgery.
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This study evaluated efficacy and safety of sugammadex 4 mg kg(-1) for deep neuromuscular blockade (NMB) reversal in patients with severe renal impairment (creatinine clearance [CLCR] <30 ml min(-1)) vs those with normal renal function (CLCR ≥80 ml min(-1)). ⋯ NCT00702715.