British journal of anaesthesia
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Comparative Study
Comparison of cardiac output measured by oesophageal Doppler ultrasonography or pulse pressure contour wave analysis.
Maintaining adequate organ perfusion during high-risk surgery requires continuous monitoring of cardiac output to optimise haemodynamics. Oesophageal Doppler Cardiac Output monitoring (DCO) is commonly used in this context, but has some limitations. Recently, the cardiac output estimated by pulse pressure analysis- (PPCO) was developed. This study evaluated the agreement of cardiac output variations estimated with 9 non-commercial algorithms of PPCO compared with those obtained with DCO. ⋯ Comité d'éthique de la Société de Réanimation de Langue Française No. 11-356.
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In the original article, under the "Declaration of Interests" section, the authors stated "none declared" since they had no direct interest in the use of local anaesthetics to treat cancer (the focus of the article being the beneficial use of local anaesthetics in cancer surgery). However, they do have a pending patent on blockers that specifically target the persistent current component of voltage-gated sodium channels, as anti-metastatic agents.