British journal of anaesthesia
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Intensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.
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Enhanced recovery programmes reduce hospitalisation and medical complications across procedures, but unfortunately there have well-documented difficulties in implementation. Some recovery programmes include many components that hinder widespread implementation. The delivery of Drinking, Eating, and Mobilising (DrEaMing) bundle, with its focus on drinking, eating, and mobilising, may serve as a simple combined process, outcome measure, or both, thereby facilitating further progress in monitoring, auditing, implementation, and improvement of enhanced recovery programmes.
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Review Meta Analysis
Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery.
Delirium is a common neurocognitive complication after cardiac surgery. The aim of this systematic review was to determine whether the administration of dexmedetomidine in the perioperative period decreases the incidence of postoperative delirium in adult patients undergoing cardiac surgery. ⋯ CRD 42021252779.