British journal of anaesthesia

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• Br J Anaesth · Jan 2025

  Reactive astrocytes mediate postoperative surgery-induced anxiety through modulation of GABAergic signalling in the zona incerta of mice.

  Surgery can induce severe neuroinflammation and negative emotional symptoms, such as anxiety-like behaviour. We studied whether reactive astrocytes in the zona incerta (ZI) mediate surgery-induced anxiety in mice. ⋯ Reactive astrocytes in the zona incerta mediate surgery-induced anxiety, possibly by regulating GAT-3-mediated GABA homeostasis and inactivating ZIGABA→median raphe nucleus projections in mice.

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• Br J Anaesth · Jan 2025

  Letter

  Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery. Response to Br J Anaesth 2024.

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• Br J Anaesth · Jan 2025

  Letter

  Induction of anaesthesia and airway management in patients with severe tracheal stenosis: a single-centre retrospective study.

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• Br J Anaesth · Jan 2025

  Letter

  Cardiac index-guided therapy to maintain optimised postinduction cardiac index in high-risk patients having major open abdominal surgery. Comment on Br J Anaesth 2024; 133: 277-287.

  no abstract available

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• Br J Anaesth · Jan 2025

  Letter

  Simulation-based learning for anaesthesia trainees in low-resource settings: the Vital Anaesthesia Simulation Training (VAST) Foundation Year.

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